IBD – general
Dietary Therapies in Pediatric Inflammatory Bowel Disease: An Evolving Inflammatory Bowel Disease Paradigm.
A review article on dietary management in IBD. Comprehensive and interesting. Read more »
A review article on dietary management in IBD. Comprehensive and interesting. Read more »
This study examined the lactulose-mannitol (LacMan) ratio in first-degree relatives of individuals with Crohn's Disease. Researchers found that the LacMan ratio was not significantly heritable suggesting that the contribution of genetic factors to the determination of intestinal permeability in healthy FDRs is modest. Read more »
In this study, researchers (1) identify a set of age-discriminatory bacterial taxa whose representations define a program of microbiota assembly and maturation during the first 2 postnatal years of twins; (2) describe a pattern of progression of gut mucosal IgA responses to bacterial members of the microbiota; and (3) assess the effects of zygosity, birth mode, and breast feeding. Read more »
This study determines that infants born through Caesarean section have a lower total microbial diversity, delayed colonisation of the Bacteroidetes phylum and reduced Th1 responses during the first 2 years of life. Read more »
We show reduced p38 MAPK activation in curcumin-treated mucosal biopsies, enhanced IL-10 and reduced IL-1b and demonstrate dose-dependent suppression of MMP-3 in CMF. We conclude that curcumin, a naturally occurring food substance with no known human toxicity, holds promise as a novel therapy in IBD. Read more »
Curcumin seems to be a promising and safe medication for maintaining remission in patients with quiescent UC. Further studies on curcumin should strengthen our findings. Read more »