Clinical Science
View by
Go to Page:

Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice

In this study, researchers (1) identify a set of age-discriminatory bacterial taxa whose representations define a program of microbiota assembly and maturation during the first 2 postnatal years of twins; (2) describe a pattern of progression of gut mucosal IgA responses to bacterial members of the microbiota; and (3) assess the effects of zygosity, birth mode, and breast feeding. Read more »

Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1b and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease

We show reduced p38 MAPK activation in curcumin-treated mucosal biopsies, enhanced IL-10 and reduced IL-1b and demonstrate dose-dependent suppression of MMP-3 in CMF. We conclude that curcumin, a naturally occurring food substance with no known human toxicity, holds promise as a novel therapy in IBD. Read more »

Go to Page:


Latest research findings regarding IBD